Global Programme 

Supporting integrated surveillance of Antimicrobial Resistance and Use through Quadripartite collaboration: Active from Dec 2025 to Dec 2027

This project aims to consolidate the Global Integrated Surveillance System of antimicrobial resistance (AMR) and antimicrobial use (AMU), (GISSA), led by the Quadripartite organizations to support and strengthen integrated One Health surveillance of AMR and AMU in countries. GISSA will develop tools, guidance, and capacity-building instruments to guide countries in the implementation and improvements of the National Integrated Surveillance System. A GISSA platform for data repository is under development following the initial progress made during the first MPTF phase, this GISSA data platform will include existing global sector specific platforms (GLASS, InFarm, ANIMUSE) and will be developed to facilitate data exchange, improve dissemination. These outcomes will enable countries to generate and use harmonized, high-quality surveillance data to design targeted interventions, strengthen multisectoral coordination, and advance sustainable context-specific national responses to AMR.

The key activities provided through the project include:

• Finalization and launching of the Global Integrated Surveillance System on Antimicrobial Resistance and Use (GISSA) and the Stage 1 of the GISSA digital platform and website
• Development of a self-assessment questionnaire for countries to identify the gaps to implement or improve capacity for integrated surveillance system of AMR and AMU
• Conducting a scoping exercise to inform the future development of Quadripartite guidance on integrated analyses and reporting of AMR and AMU data, building on existing resources and informed by preliminary mapping of country capacities

Anticipated outcome:

Countries will develop the capacity to design and implement evidence informed One Health strategies to combat AMR in a sustainable manner. The project will enhance existing systems and structures per sector, including institutional capacities, to support the consistent and effective implementation of country-led AMR response following a One Health approach. As a result, countries will be better equipped to coordinate multisectoral efforts, allocate resources efficiently, and adapt strategies based on local data and needs, leading to a more resilient AMR response.

For more information, visit: One Health Integrated Surveillance of AMR and AMU

Closing the Gap on One Health Needs for Evidence on Antimicrobial Resistance through Research Active from Dec 2025 to Dec 2027

Multisectoral One Health research, which integrates efforts across humans, animals, plants and environment sectors, is key to address AMR. This Research component supports multisectoral and interdisciplinary research from a local level perspective to fill knowledge gaps identified by the scientific community in the One Health Priority Research Agenda for AMR (AMR-OHPRA). Launched in 2023, the AMR-OHPRA includes 62 research areas across five thematic pillars: transmission, integrated surveillance, interventions, behavioral insights and change, economics and policy.

The key activities provided through the project include:

• Design, launch and manage research grant calls to support multisectoral teams in AMR MPTF countries for conducting scientific studies that answer global knowledge priorities aligned as in the AMR-OHPRA while tailored to local contexts.
• Support and monitor implementation of funded research projects, ensuring technical guidance coordination and links between the local and global research communities.
• Promote uptake and contribution of research findings including the dissemination of results at both national and global AMR level (i.e. publications, webinars).
• Pilot and validate approaches to support the generation of relevant, science-based evidence at country level, contributing to the global knowledge and interdisciplinary AMR response.

Anticipated outcome:

Strengthened generation, sharing, and use of scientific evidence through the design and implementation of multisectoral research studies aligned with global One Health AMR research priorities. The project will also support science-policy-practice dialogue, multi sectoral coordination and science-based national AMR response tailored to country-specific needs in line with their National Action Plans on AMR.

For more information, visit: One Health Priority Research Agenda for AMR

Catalyzing multisectoral efforts and collaboration to implement UNGA political declaration commitments through One Health approach

More information coming soon

Strengthening the monitoring and evaluation of Multisectoral National Action Plans on AMR, the Global Action Plan on AMR, and the UNGA HLM on AMR political declaration commitments

More information coming soon

Implementation and Dissemination of the Quadripartite One Health Legislative Assessment Tool for AMR

More information coming soon